摘要
[目的]探讨广东地区前列腺癌与饮食因素的病因学关联。[方法]在中山大学四所附属医院开展一项病例对照研究(1︰2配对),匹配条件为年龄组(±5岁)、性别、民族和居住地类型相同。调查以面谈为主,辅以病历记录,采用条件Logistic回归法分析数据。[结果]以前列腺增生为对照,每月至少吃1次鸡肉可以增加患前列腺癌的危险,OR=2.74(0.67-11.16);常吃玉米和叶类蔬菜有助于预防前列腺癌,OR玉米1～4次/月=0.31(0.13-0.76),OR蔬菜每天=0.42(0.13-1.40)。以其他疾病为对照,每月吃鸡肉者患前列腺癌的危险是偶尔/从未食用者的2.70(0.66-11.00)倍;常喝牛奶和常吃动物内脏也增加患前列腺癌的危险,OR牛奶1～6次/周=2.56(0.80-8.16),OR动物内脏1～6次/周=9.07(1.10-74.64);常吃玉米、块茎类蔬菜和水果有助于降低患前列腺癌的危险,OR玉米1～4次/月=0.54(0.23-1.22),OR块茎类蔬菜1～4次/月=0.38(0.12-1.28),OR水果1～4次/月=0.15(0.023-0.96)。[结论]本研究提示摄入过多的鸡肉、牛奶和动物内脏是前列腺癌的危险因素,多吃玉米、蔬菜和水果有利于降低前列腺癌的危险。
[Objective] To explore the causal association between prostate cancer and dietary factors among Cantonese. [Methods] A hospital-based ease-control study was conducted from 2005 to 2006 in four affiliated hospitals of Sun Yat-sen University in Guangzhou. The cases and controls were matched by age （± 5 years） , gender, nation and resident location. All the subjects were interviewed face to face in the hospitals by experienced investigators. The data were analyzed with Conditional Logistic Regression Model. [ Results] When BPH was used as control, more consumption of chicken increased the risk of prostate cancer （OR1-4 times per month= 2.74, 95%, CI： 0.67-11.16） . Eating more maize and green vegetables reduced the risk of prostate cancer, compared with the lowest quartile （ORmaize 1-4 times per month= 0.31, 95% CI： 0.13-0.76, ORgreen wegetables=0.42, 95%CI 0.13-1.40） . When other diseases was used as control, more consumption of chicken promoted the risk of prostate cancer （OR1-4 times per month= 2.69, 95%CI 0.66-1 1.00） . A positive association was observed between prostate cancer and milk consumption or pluck consumption （ORmild 1-6 times per week= 2.56, 95%CI： 0.80-8.16, ORPluek1-6 times per week= 9.07, 95%CI： 1.10-74.64） . High consumption of maize, stem tuber vegetables and fruits reduced the risk of prostate cancer compared with the lowest quartile （ORmaize1-4 times per month= 0.54, 95%CI： 0.23-1.22, ORstem tuber vegetables= 0.42, 95%CI： 0.13-1.40, ORfruits1-4 times per month= 0.15, 95%CI： 0.023-0.96） . [Conclusion] This study suggests that more consumption of chicken, milk and pluck may increase the risk of prostate cancer. High consumption of maize, vegetables and fruits lower the risk of prostate cancer.
出处
《现代预防医学》
CAS
北大核心
2007年第9期1646-1649,1655,共5页
Modern Preventive Medicine
