摘要
青光眼滤过手术失败的主要原因之一是手术后术区成纤维细胞增殖、胶原沉积、滤过泡瘢痕形成,多年来,人们寻找了许多术后抗瘢痕形成的药物和方法来延长滤过泡寿命,提高手术成功率。其中一些已经用于临床,但这些药物和方法也有其不足之处,应用不慎时还会带来一些负面效应。正确的评价和合理的使用它们非常重要。寻找更新的药物和方法仍是目前青光眼研究的方向之一。
One of the major reasons of the failure after glaucoma filtration surgery is the proliferation of fibroblast, the deposition of collagen and the scar of bleb. Many scientists racked their brains and managed to find many drugs and methods to prolong the life of bleb and improve the successful rate of the operation for many years. Some of them have already been used dinically. Meanwhile, they also have shortcoming and even induce some negative effectives without correct application. It is very important to evaluate them correctly and select them rationally. Searching new drugs and methods is still one of the researching directions of glaucoma at present.
出处
《国际眼科杂志》
CAS
2007年第2期464-468,共5页
International Eye Science
