摘要
目的观察碱性成纤维细胞生长因子(bFGF)对外伤性鼓膜穿孔的治疗效果。方法随机将外伤性鼓膜穿孔分为两组:治疗组66例,用浸湿bFGF的压薄无菌棉片贴补,并每日两次用bFGF喷耳;对照组22例仅用贴补治疗。结果治疗4周后,治疗组鼓膜穿孔愈合率为98.3%,平均愈合时间为10.6天;对照组鼓膜穿孔愈合率为63.6%,平均愈合时间为22.2天。结论bFGF浸湿棉片贴补加喷耳治疗外伤性鼓膜穿孔可促进穿孔愈合,缩短愈合时间。
Objective To observe the healing effects of basic fibroblast growth factor （bFGF） on traumatic tympanic membrane perforations. Methods In 98 cases of traumatic tympanic membrane perforations, 66 patients were treated with cotton patches soaked with bFGF applied to the surfaces of perforated tympanic membrane and bFGF eardrop was driped onto the patches twice per day, other 22 patients without the use of bFGF as the control. Results Of 66 patients treated wit bFGF, 65 had healed perforations, the closure rate of tympanic membrane perforations was 98.3% and the average healing time was of 10.6 days in bFGF group. While in control group , the closure rate of tympanic membrane perforations was 62.5% and the average heating time, 22.2 days. Conclusion It is showed that bFGF patching is effective at treating traumatic tympanic membrane perforations.
出处
《中华耳科学杂志》
CSCD
2007年第1期49-51,共3页
Chinese Journal of Otology
关键词
鼓膜穿孔
外伤性
碱性成纤维细胞生长因子
Tympanic membrane perforation, traumatic
Basic fibroblast growth factor
