摘要
采用Er:YAG激光(波长为2 940 nm,能量密度为:2.5 J/cm2单光斑,扫描次数为4)照射活体小白鼠皮肤,利用光学相干层析成像(optical coherence tomography,OCT)技术在活体小鼠上观察其皮肤组织在激光作用之前及作用之后光热损伤修复的整个过程,得到了激光光热作用下引起损伤的皮肤组织在此过程中皮肤光学特性参数的变化情况,发现皮肤修复过程中光学参数有显著差异,并分析了这些差异引起的原因,以揭示激光美容中并发症主要因素。
Er： YAG laser （2 940 nm, 2.5 J/cm^2, single spot, 4 times） was irradiation on a mouse skin in vivo, and the skin which before irradiation and the process of renovating scathe that irradiated after Er： YAG laser were observed by an optical coherence tomography （OCT）. The results indicate that the optical parameters of post-laser irradiation tissue have changed distinctly. The reasons concerning some complications were analyzed by the optical parameters＇ changes and the major factors of the complications in laser skin rejuvenation were expected to be found.
出处
《激光生物学报》
CAS
CSCD
2007年第2期163-166,共4页
Acta Laser Biology Sinica
基金
教育部高校优秀青年教师资助计划/新世纪优秀人才支持计划资助(NCET-04-0615)
关键词
光学相干层析成像技术
热损伤
监测
optical coherence tomography（QCT）
thermal damage
monitor
