摘要
用ＥＬＩＳＡ法对７８例非系统性红斑狼疮（ＳＬＥ）脑梗塞患者和３８例正常对照组ＡＣＡ进行检测，初步探讨了ＡＣＡ与脑梗塞的关系及ＡＣＡ阳性脑梗塞的临床特征，结果发现：ＡＣＡ与脑梗塞的发病有关，ＡＣＡ阳性脑梗塞具有发病年龄偏轻，易复发的特点；ＡＣＡ阳性病例组与ＡＣＡ阴性病例组对比痴呆的发病率无显著差异；ＡＣＡ阳性脑梗塞患者ＣＴ图像无特征性改变。以上结果提示，检测ＡＣＡ对缺血性脑血管病的预防和治疗有一定价值。
To demonstrate the relation between ACA and cerebral infarct and the clinic feature of ACA positive cerebral infarct,this experiment measured ACA level by enzyme linked immunosorbent assay(ELISA) in 78 patients without evidence of SLE who suffered cerebral infarction and 38 healthy controls.The results showed that ACA had some relation with the occurrence of cerebral infarction.The mean age when they had the first attack of stroke was significantly younger,the history of recurrent cerebral infarct was more frequent in ACA positive patients.No difference were noted in dementia rate between ACA positive and negative groups no significant feature was found in CT imaging of ACA positive cerebral infarction.It is suggested that measuring ACA maybe have some value in treating and preventing ICVD.
出处
《中国免疫学杂志》
CAS
CSCD
北大核心
1997年第1期54-56,共3页
Chinese Journal of Immunology
