摘要
目的观察尿激酶介入治疗血管源性突发性耳聋的临床疗效。方法65例突发性耳聋患者分为治疗组35例和对照组30例，治疗组采用尿激酶经介入导管注入椎-基底动脉从而进入迷路动脉，改善内耳微循环，对照组采用传统静脉给药治疗。应用纯音测听等手段检查两组患者治疗前后的听力变化，比较疗效。结果治疗组21例听力恢复正常，12例听力提高15～30dB，2例提高〈15dB；对照组10例恢复正常，4例提高15～30dB，9例提高〈15dB，7例无明显变化，治疗组疗效优于对照组（P〈0.05）。结论尿激酶介入治疗突发性耳聋效果优于传统静脉给药方法。
Objective To observe the effect of interventional therapy of urokinase on sudden hearing loss. Methods 65 patients with sudden hearing loss were divided into the treatment group （n= 35） and control group （n= 30）. The patients of the treatment group were treated with urokinase pouring into vertebral artery accordingly into labyrinthine artery in order to improve internal ear microcirculation. Those of the control group were treated with routine drug dropping in vein. All patients of two groups were examined by pure tone test before and after treatment and the therapeutic effect of two groups was compared. Results In the treatment group, the audition of 21 cases recovered, 12 cases got 15～30 dB increasing, 2 cases increased 〈15 dB. In the control group, the audition of 10 cases recovered, 4 cases got 15～30 dB increasing, 9 cases increased 〈15 dB and 7 cases had no obvious improvement. There was a significant difference between effects of two groups （ P 〈0.05）. Conclusion The effect of urokinase on sudden hearing loss is superior to routine drug dropping in vein.
出处
《中国康复理论与实践》
CSCD
2007年第4期395-396,共2页
Chinese Journal of Rehabilitation Theory and Practice
关键词
突发性耳聋
介入治疗
尿激酶
sudden hearing loss
interventional therapy
urokinase
