摘要
目的:研究不稳定性心绞痛患者血浆溶血磷脂酸(LPA)水平的改变,探讨葛丹稳心汤从痰瘀同治对不稳定性心绞痛患者的临床疗效。方法:将138例患者随机分为治疗组97例和对照组41例,治疗组应用葛丹稳心汤和西药常规治疗,对照组单用西药常规治疗,且两组治疗前后均检测心电图、血脂、血液流变学指标及LPA。结果:治疗后治疗组的心电图、血脂、血液流变学指标和LPA的变化情况与对照组比较均有显著性差异(P<0.05)。结论:LPA在不稳定性心绞痛患者的血浆中可显著升高,并对不稳定性心绞痛患者的发病、治疗和预后有重要影响;葛丹稳心汤确能改善心肌缺血,增加冠脉流量,抑制血小板集聚和清除冠状动脉内的血栓。
Objective： To study the changes of LPA in patients with unstable angina and discuss the clinical effects on unstable angina treated by Gedan Wenxin decoction with treating phlegm and blood stasis therapy. Method： 138 cases were randomly divided into 97 cases in the treatment group and 41 cases in the control group. Cases in the treatment group were treated by Gedan Wenxin decoction and routine western medicine, cases in the control group treated only by routine western medicine. ECG, blood-lipid, indexes of blood rheology and LPA in the two groups were detected before and after treatment. Results ： The improvement of ECG, blood - lipid, indexes of blood rheology and LPA in the treatment group had significant difference as compared with that in the control group （ P 〈 0.05 ）. Conclusion： The rise of LPA in patients with unstable angina was important for invasion, treatment and prognosis. Gedan Wenxin decoction had definite effects of improving myocardial ischemia, increasing flow rate of coronary artery, restraining platelet aggregation and clearing thrombus in coronary artery.
出处
《湖南中医杂志》
2007年第2期5-7,共3页
Hunan Journal of Traditional Chinese Medicine
关键词
心绞痛
不稳定型
中西医结合疗法
磷脂酸类
葛丹稳心汤
Unstable angina
Integrated Chinese traditional and western medicine
LPA
Gedan Wenxin decoction
