摘要
小肠黏膜下层是天然细胞外基质类生物衍生材料,对其力学性质的描述在组织工程研究中非常必要。在对SIS的单轴拉伸测试中,很难确定合适的参考状态,也没有一个被广泛认可的公式来表达其应力应变关系。针对这些问题,本研究提出了力学关系重建和二次拟合技术。对于原始试验数据,用二次多项式拟合应力应变关系,根据拟合抛物线的最低点确定参考状态。在参考状态下,对原始数据重新计算出新的应力应变值,最后用缺省常数项的二次式对其关系进行第二次拟合。所有过程通过平均相对误差e来同其它公式衡量比较。大量实验数据证明这是一种切实有效的处理方法。
Small-intestinal submucosa （SIS） is a material derived from natural extracellular matrix （ECM）. Describing its biomechanical property is indispensable in tissue engineering. But it is difficult to make certain proper reference state in the uniaxial tensile test, and there has not been an acceptable formula to express its stress-strain relationship. This study proposed the mechanical relationship reconstruction and second fitting technology. Quadratic polynomial was used to fit the original data for the stress-strain relationship, and the minimum point of the fitting parabola was defined as reference state. Under this state, all the original data were recalculated to new values of stress and strain, then fit them for the second time with the quadratic expression without constant term. All processes were compared with other formulae by the mean relative error. This method is confirmed as a valid means by many experiment data.
出处
《中国生物医学工程学报》
CAS
CSCD
北大核心
2007年第2期265-269,共5页
Chinese Journal of Biomedical Engineering
关键词
小肠黏膜下层
单轴拉伸测试
参考状态
应力应变关系
small-intestinal submucosa
uniaxial tensile test
reference state
stress-strain relationship
