摘要
目的:探讨加替沙星致不良反应的特点及一般规律,为临床合理用药提供参考。方法:对1999～2006年国内、外主要医药期刊报道的754例和我院上报的35例加替沙星不良反应进行统计、分析。结果:加替沙星不良反应主要有胃肠道反应、神经系统反应、皮肤及附件损害、糖代谢异常、心血管系统反应、肝毒性、过敏性休克等。结论:临床应重视加替沙星不良反应的危险性。
OBJECTIVE：To investigate the characteristics and patterns of ADR induced by gatifloxacin for the purpose of providing reference for rational use of drugs.METHODS： 754 gatifloxacin- induced ADR cases reported in major Chinese and overseas medical ＆ pharmaceutical iournals from 1999 to 2006 were audited and analyzed together with 35 cases collected from our hospital.RESULTS： Gatifloxacin- induced adverse reactions range from gastrointestinal disturbances, nervous system Complaints, skin ＆ its appendages impairment, disturbance of carbohydrate metabolism, hepatotoxicity, cardiovascular complaints to allergic shock.CONCLUSION：Great attention should be paid to the antibacterial effect of gatifloxacin and the danger resulted from its adverse reactions.
出处
《中国药房》
CAS
CSCD
北大核心
2007年第11期866-867,共2页
China Pharmacy
关键词
加替沙星
不良反应
分析
Gatifloxacin
Adverse reaction
Analysis
