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滋养层细胞凋亡及其调控因素与稽留流产关系的研究进展 被引量:6

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摘要 细胞凋亡(apoptosis)是个体发育过程中基因调控下的细胞自杀活动.是多细胞有机体为调控机体发育,维护内环境稳定,由基因编码程序的细胞主动死亡过程。细胞凋亡是机体对外界刺激进行主动应答的过程,可见于胚胎发育,正常组织代谢和某些病理情况。稽留流产(missed abortion),又称过期流产,指宫内胚胎或胎儿死亡后未及时排出者。造成稽留流产的原因较多:首先是胚胎本身发育异常.包括了父母双方的精子和卵子基本结构-染色体的数量、结构等异常,其次是子宫内环境异常.内分泌功能紊乱,免疫功能不全及过量吸烟等不良习惯影响.再者是全身性感染疾病、严重营养缺乏、环境不良因素及创伤等。持续而大量的应用孕激素治疗先兆流产.也可能是导致稽留流产的原因之一。
出处 《江西医药》 CAS 2007年第2期173-176,共4页 Jiangxi Medical Journal
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参考文献17

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二级参考文献39

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