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盐酸倍他司汀对椎基底动脉供血不足性眩晕的疗效观察

Therapeutic Effects of Batahistine for Treatment of 31 Patients with Vertebrobasilar Insufficiency
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摘要 目的观察盐酸倍他司汀治疗椎基底动脉供血不足(VBI)性眩晕的疗效。方法对64例VBI眩晕患者随机分为治疗组与对照组各32例,均于发病24h内治疗。治疗组应用盐酸倍他司汀20mg加复方丹参注射液20ml;对照组维脑路通400mg加复方丹参注射液20ml,静脉点滴,1次/d,疗程14d。应用经颅多普勒(TCD)测定治疗前后椎动脉(VA)、基底动脉(BA)、大脑后动脉(PcA)血流速度.结果治疗组总有效率为96.8%,对照组总有效率为72.8%,两组有显著差异(P〈0.01)。TCD检查治疗组用药后VA等血流速度与用药前比较明显改善,与对照组相比有显著差异(P〈0.01)。结论倍他司汀治疗VBI疗效确切。 Abstracti Obiective To observe the therapeutic effect ofbatahistine on vertebrobasilar insufficiency(VBI). Methods Sixty Four VBI patients were divided randomly into therapeutic group and control group, all of whom received treatment within 24hours after VBI seizure, In the therapeutic group, batahistine 20mg+20ml salvia injection was given intravennously once a day, for 14days. In control group. 400mg wenoruton+20ml salvia injection was given intravenously once a day, for 14days The tachography was performed in two groups, including mean blood flow velocity of vertebral artery(VA), basilar artey(BA), Posteriorcerebral artery(PCA), by transcranall Doppler ultresonography before and after treatment. Results The total effective rateintherapeutic group and control group was 96.8 % and 72.8 % respectively(P〈 0.01). In the therapeutic group, the mean blood flow velocity of VA, BA and PCA were obviously improved after treatment compared with therapeutic control group(P 〈 0.01 ). Conclusion The betahistine has a convinced curative effect for VBI patients.
出处 《中华临床医学杂志》 2007年第2期17-18,共2页 Chinese Journal of Clinical Practical Medicine
关键词 倍他司汀 椎基底动脉供血不足 Batahistine Vertebrobasilarinsufficiency
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