摘要
1982~1995年间,在555例BPH术后标本中,发现IDPC24例。1982~1991年,用常规方法的诊断率为1.6%(5/310),1992~1995年用垂直于尿道连续大切块,诊断率为7.5%(19/245)。镜下特征为(1)癌灶与增生组织之间无明显分界(100%);(2)多与不典型增生共存(16/24);(3)常为多发癌灶(20/24);(4)癌灶多位于中央区(20/24)。按Mostofi's系统分级,Ⅰ级8例,Ⅱ级12例,Ⅲ级4例,而4例Ⅲ级者均不伴不典型增生。资料显示:标本的取材方法与IDPC的诊断率密切相关,IDPC的发病率伴随BPH逐年同步增加。文中对IDPC的发生学及与BPH的关系作了进一步讨论。
During 1982 ̄1995,24 patients with incidentally discovered prostatic carcinoma (IDPC) were identified among 555 samples of post-operative benign prostatic hyperplasia (BPH).By routine method,the diagnostic rate was 1.6% (5/310) in 1982 ̄1991.By a method with gross sample continuous section perpendicular to urethra,the diagnostic rate was 7.5% (19/245) in 1992 ̄1995.Microscopic characters:(1)The dividing line between canceration focus and proliferative tissue is not clear.(2)The majority of IDPCs follow atypical hyperplasia.(3) Canceration focus is polycentric. (4) Canceration focus often is localized in the central zone of prostate around the urethra. 4 patients with the carcinoma at the third Mostofi's grade was not accompanied by atypical hyperplasia.The data show that the diagnostic rate of IDPC is closely related to the management of samples.Following BPH, with ageing the morbidity of IDPC increases synchronously year by year.The relationship between the pathogenesis of IDPC and BPH was discussed in detail.
出处
《诊断病理学杂志》
CSCD
1996年第4期205-206,共2页
Chinese Journal of Diagnostic Pathology
关键词
前列腺偶发癌
病理诊断
前列腺癌
Incidentally discovered prostatic carcinoma
Pathological diagnosis