摘要
观察了51例急性心肌梗死病人静脉应用尿激酶治疗后，冠状动脉再通组及未通组心电图ST段以及血清肌酸激酶（CK）和肌酸激酶同功酶（CK－MB）的变化规律，并对血管再通组及未通组的临床疗效进行了分析。结果表明：急性心肌梗死病人经静脉溶栓治疗后，冠脉再通组的心电图ST段在用药后30min开始下降，90min下降达53．1％，与未通组心电图ST段具有显著差异；冠脉再通组血清CK及CK－MB在胸痛后14h达到高峰，而未通组在胸病后20h达到高峰；冠脉再通率为67％，再通组心力衰竭、心律失常及病死率明显低于未通组。AMI病人早期经静脉应用溶栓剂治疗，可改善急性期预后，应积极推广。
Coronary reperfusion rate and unreperfusion rate were observed in 51 patients with acute myocardial infarction through venous urokinase therapy. The patients were divided into two groups according to 50% of ST segment decrease at 2h after treatment, early rise of creatine kinase (CK) during 16h and CK-MB during 14h after chest pain. The result showed that the persentage of ST segment started to reduce in 30 min. It reduced by 53.1% in 90min, Showing a significant difference between two groups. The time of early rise of CK and CK-MB was 14h after chest pain in reperfusion group and 20h in unreperfusion group,Coronary reperfusion rate was 67%. Mortality and complicated rate in reperfusion group was significantly lower than that of unreperfusion group. It was concluded that thrombolytic therapy had important prognostic implication for survival after acute myocardial infarction and therefore, should be spread extensively.
出处
《急诊医学》
CSCD
1996年第4期197-200,共4页
关键词
急性
心肌梗死
尿激酶
溶栓治疗
Acute myocardial infarction Urokinase Creatine kinase MB isoenzyme of creatine kinase
