摘要
为了观察中药圣和散对胃癌手术后复发、转移率的影响，１３６例胃癌根治术后患者随机分为治疗组和对照组。治疗组７５例采用圣和散联合化疗治疗，对照组６１例采用单纯化疗。随访２～４年。结果：治疗组复发率１２．０％，转移率１７．３％，对照组复发率２３．０％，转移率３６．１％，两组比较有显著差异（Ｐ＜０·０５）１、２、３年生存率治疗组依次为９３．３％、８５．３％和８１．３％，明显优于对照组的７３．８％、６３．６％和５５．７％（Ｐ＜０．０１～０．００５）。同时发现，治疗组中气阴两虚型的复发、转移率明显高于其它证型。作者认为，圣和散联合化疗能明显降低胃癌术后复发与转移，提高远期疗效，是胃癌术后综合治疗值得探索的途径。
nordertoinvestigatetheeffectsofShenghepowder(SHP)forpostoprativegastriccan-cer,fromOctober,1991toAprll,1994,136patientswithgastriccancerafterrudimentalsur-gicaloperationswererandomlydividedintotreatinggroup(75cases)andcontrolgroup(61cases).ThePatientsintreatinggroupreceivedSHPtherapypluschemotherapy,andthepa-tientsincontrolgroupweretreatedwithchemotherapyalone.Thefollow-upresultsshowedthattherecurrenceandmetastaticrateintreatinggroupwere12.0%* and17.3%* respective-ly,significantlylowerthanthatof23.0%* and36.1%* inthecontrolgroup(P<0.05).The1-,2-,3-year-survivalrateintreatinggroupwere93.3%* ,85.3%* and81.3%* respectively.Theywere73.8%* ,63.9%* and55.7%* inthecontrolgroup(P<0.01～0.005).Meanwhile,therecurrenceandmetastaticrateforQi-YinDeficiencytypeintreatinggroupaccordingtoChineseSyndromeDifferentiationtypingweresignificantlyhigherthanthatofothertypes(P<0.01).TheseresultssuggestedthatSHPpluschemotherapycouldmarklyreducethere-currenceandmetastaticrateofpostoperativegastriccancerandimprovesurivalperiodandmightbeahopefultherapyforpatientsofpostoperativegastriccancer.
出处
《中国中西医结合外科杂志》
CAS
1996年第6期402-404,共3页
Chinese Journal of Surgery of Integrated Traditional and Western Medicine
关键词
胃癌
术后
圣和散
复发
肿瘤转移
postoperativegastriccancer,Shenghepowder,recurrence,metastasis.
