摘要
目的:研究消风散对小鼠Ⅳ型变态反应中皮肤超微结构的作用。方法:应用2,4-二硝基氯苯(DNCB)外涂造成小鼠皮肤Ⅳ型变态反应模型,采用电镜观察实验各组小鼠皮肤真表皮超微结构变化。结果:Ⅳ型变态反应可致小鼠皮肤角质细胞电子密度略增强,棘细胞与基细胞均出现细胞萎缩,间隙增宽。胞质内细胞器呈空泡样改变。消风散组小鼠皮肤各层组织结构规则,各层组织改变程度明显减轻。结论:消风散可改善Ⅳ型变态反应对小鼠皮肤超微结构的影响,具有抗Ⅳ型变态反应的作用。
Objective： To study the effects of Xiao Feng Powder on ultrastructure of skin in delayed hypersensitivity. Methods： Delayed hypersensitivity induced by DNCB. The effects of Xiao Feng Powder on ultrastructure of skin were observed. Results： Kin tissues of the model mice appeared electronic-density of cells heightening. Prickle cell and basal cell showed cellular atrophy. Cell clearance swelled. Organelle came forth vacuolar degeneration. Xiao Feng Powder could inhibit those changes. Conclusion： Xiao Feng Powder could improve ultrastructural alteration in skin. So that Xiao Feng Powder has the function of inhibiting delayed hypersensitivity.
出处
《辽宁中医药大学学报》
CAS
2007年第2期29-30,共2页
Journal of Liaoning University of Traditional Chinese Medicine
关键词
消风散
Ⅳ型变态反应
皮肤
超微结构
Xiao Feng Powder
delayed hypersensitivity
skin
ultrastructure
