摘要
目的:研究金雀根中具有抗骨质疏松活性的异黄酮成分。方法:利用各种柱色谱分离方法得到化合物,再用波谱技术鉴定其结构。结果:分离得到6个异黄酮类化合物,分别鉴定为6,3′-二甲氧基-7,5′-二羟基异黄酮(1),(-)maackiain(2),dalbergioidin(3),3′-甲氧基-5′-羟基异黄酮-7-O-β-D-葡萄糖苷(4),Wistin(5),tri-folirhizin(6)。结论:化合物1为新化合物,其他均首次从该植物中分离得到。
AIM： To study the isoflavonoid constituents with anti-osteoporosis activity from the roots of Caragana sinica. METHOD： The compounds were isolated by means of column chromatography, and their structures were determined by spectral analyses. RESULT： Six isoflavonoid components were obtained and identified as 6,3＇-methoxy-7,5＇-dihydroxyisoflavone （1）, （-）maackiain （2）, dalbergioidin （3）, 3＇-methoxy-5＇-hydroxyisoflavone-7-O-β-D-glucoside （4）, wistin （5）, trifolirhizin （6）. CONCLUSION： Compound I is a new compound, and the others have been isolated from Caragana sinica for the first time.
出处
《中国天然药物》
SCIE
CAS
CSCD
2007年第2期101-104,共4页
基金
国家自然科学基金项目(No.39270800)~~
关键词
锦鸡儿
金雀根
异黄酮
抗骨质疏松
Caragana sinica
Jinque Gen
Isoflavonoids
Anti-osteoporosis
