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术前肾动脉化疗栓塞及术后免疫治疗巨大肾癌的疗效观察 被引量:3

The study of preoperative chemo-embolization and postoperative usage of α-interferon in the treatment of renal cell carcinoma
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摘要 目的:评价根治术前化疗栓塞及术后免疫治疗巨大肾癌的疗效。方法:回顾性分析20例经术后病理检查证实并获随访的巨大肾癌患者的临床资料。分为A、B两组。术前化疗栓塞而术后免疫治疗组12例(A组),单纯根治术组8例(B组)。结果:A组术中出血量150~400ml,平均210ml。少于B组。A组1、3年生存率分别为90.0%、80.0%。B组1、3年生存率分别为66.7%、50.0%。两组比较,差别均有统计学意义(P〈O.05)。结论:根治术前化疗栓塞及术后免疫治疗安全有效,是影响巨大肾癌预后的因素。对巨大肾癌的治疗及预后有积极意义。 Objective:To study the effect of preoperative chemo embolization and postoperative usage of α-interferon in the treatment of renal cell carcinoma. Methods: The clinical data of 20 cases with large renal cell carcinoma(〉10 cm) were analyzed retrospectively. A group were treated by preoperative chemo embolization and postoperative usage of a-interferon, B group with radical nephrectomy alone. Results: The bleeding volume of A group ( 150 - 400 ml) were less than that of the control group, the 1 year (90.0 % ) and the 3 year (80.0 % ) survival rate in patients of the study group were higher than that of the control group ( P 〈0. 05). Conclusions: Preoperative chemo-embolization and postoperative usage of a interferon is an effective means in treatment of large renal cell carcinoma and has better prognosis.
出处 《临床泌尿外科杂志》 2007年第3期207-209,共3页 Journal of Clinical Urology
关键词 肾肿瘤 化学栓塞 肾癌根治术 干扰素 Renal carcinoma Chemo-embolization Radical nephrectomy Interferon
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  • 1潘柏年,徐仁方,郭晓,何志嵩,杨勇,张晓春,周利群,郝金瑞,那彦群,薛兆英,郭应禄.肾癌525例临床分析[J].中华泌尿外科杂志,2000,21(3):135-137. 被引量:85
  • 2Tourani J M, Pfister C, Tubiana N, et al. Subcutaneous interleukin-2 and interferon alfa administration in patients with metastatic renal cell carcinoma: final results of SCAPP Ⅲ, a large, multicenter, phase Ⅱ,nonrandomized study with sequential analysis design-the Subcutaneous Administration Propeukin Program Cooperative Group[J]. J Clin Oncol, 2003,21:3987-3994. 被引量:1
  • 3Zielinski H, Smaigielski S, Petrovich Z. Comparison of preoperative embolizatiou followed by radical nephrectomy with radical nephrectomy alone for renal cell carcinoma[J]. Am J Clin Oncol, 2000,23: 6 - 12. 被引量:1
  • 4马建辉,鲍镇美.干扰素治疗肾癌[J].中华泌尿外科杂志,2003,24(6):429-431. 被引量:17

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