摘要
目的了解泌尿生殖道感染就诊的拟诊非淋菌性尿道炎(NGU)患者的常见病原体的感染特征,探讨影响非淋菌性尿道炎流行的相关因素。方法收集拟诊NGU患者的尿道/阴道分泌物标本,进行沙眼衣原体(Ct)、解脲支原体(Uu)、人型支原体(Mh)、淋病奈瑟菌(Ng)、念珠菌(Cd)、滴虫(Tv)、单纯疱疹病毒Ⅱ型(HSV-2)等常见病原体的检测与培养。同时对患者进行结构式问卷调查。结果977例被检者中,Ct阳性329例(33.67%),Uu156例(15.97%),Mh72例(7.37%),Ng25例(2.56%),Cd46例(4.71%),Tv28例(2.87%),HSV-2 7例(0.72%)。同时有两种或两种以上病原体混合感染的98例(10.03%),其中有两种病原体混合感染的为88例,主要为Ct、Uu、Mh、Ng间的混合感染。在Ct、Uu阳性检出者中25.85%为无症状感染。有90%NGU患者感染于18-49岁性活跃期年龄组,其中以30-39岁感染居多;Ct、Uu、Cd的检出率女性高于男性。非婚性接触感染占NGU的65.30%。结论(1)拟诊NGU患者其病原体感染检出率较高的有衣原体、支原体、淋病奈瑟菌、念珠菌(χ2=68.39,P<0.005);(2)在NGU患者中存在有两种或两种以上病原体的混合感染;(3)无症状的NGU感染者应引起临床高度重视;(4)NGU的流行和传播与多种危险因素有密切关系。
Objective To analyze the pathogenic characteristics of Chlamydia, Mycoplsma, Neisseria gonorrhoeae, Trichomonas,Candida and Herpes simplex virus in patients with urogenital infections and study the relevant influential factors. Methods Genital secretions of the patients who were suspicious of non gonocoecal urethritis（NGU）were collected as samples to detect and cultivated Chlamydia trachomatis（Ct）, Ureaplasma urealyticum（Uu）, Mhominis（Mh）, Neisseria gonorrhoeae （Ng）,Candida（Cd）, Trichomonies and the type 2 Herpes virus.At the same time,surveys with structured questionnaire were conducted. Results In the 977 detected patients,the rate of positive expression of Ct was 33.67% （329/977） ,Uu- 16.1% （156/977） ,Mh- 7.36% （72/977） ,N - 2.56% （25/977）, Cd- 4.7% （46/977） ,Tv- 2.87% （28/977）, and FIBS - 2 - 0.72 % （7/977）. The rate of co-infections of two or more pathogens （mainly between Ct, Uu, Ng ang Cd）was 10.03（98/977）. About 25.85 % of the patients in the positive Ct and Uu group were infected without symptom. 90 % of NGU patients were sex active, aged 18- 49 years and most of infections occurred in age group of 30 39 years. Positive rate of Ct,Uu and Cd was higher in females than in males. The infection rate due to ex-marital sexual contact was 65.30 % among all the NGU patients. Conclusions （1）The Ct,Uu, Ng and Cd have a higher positive detection rate in the NGU patients in the STD clinic. （2）Co-infection with two or more pathogens are common in the NGU patients. （3）We should pay more attention to the patients with no symptoms. （4）Epidemics and transmission of NGU is largely related with a number of risk factors.
出处
《中国艾滋病性病》
CAS
2007年第1期50-51,63,共3页
Chinese Journal of Aids & STD
基金
山西省教育厅2003年攻关课题资助项目
