摘要
目的评价中药夏氏睡眠1号治疗虚证型失眠症患者的疗效与安全性。方法将120例符合CCMD-3诊断标准和中医辨证为虚证型的失眠症患者随机分为两组,每组60例。治疗组给予中药夏氏睡眠1号,对照组给予艾司唑仑1mg,共治疗6周。采用阿森斯失眠量表(AIS)及病情严重程度评定临床疗效,用副反应量表(TESS)评定不良反应。结果治疗组总有效率为80%,略高于对照组(70%),但差异无显著性意义(P>0.05);对长期失眠的治疗,治疗组有效率为77.8%,对照组为52.4%,差异有显著性意义(P<0.05)。治疗组的不良反应明显比对照组少而轻。结论夏氏睡眠1号方药对于属中医虚证型的失眠症患者有效且无明显毒副作用。
Objective To evaluate the therapeutic effect and safety of Xia＇s Sleep No. 1 for insomnia of deficiency pattern. Methods Totally 120 cases of insomnia according to Chinese Classification of Mental Disorders Version 3 （CCMD-3） criteria with deficiency syndrome were randomly divided into two groups. Xia＇s Sleep No. 1 was given to 60 patients in the treatment group ,while lmg of Estazolam was taken in the control group. The treatment course lasted for 6 weeks. Clinical effect was evulated by Athens Insomnia Scale （AIS） and pathogenetic condition,while adverse effect by Treatment Emergent Symptom Scale （TESS）. Results The total effective rate of the treatment group （80%） was higher than that of the control group （70%）;but there was no significant difference between both groups （P〉0.05）. The effective rate on long-term insomnia of the treatment and control group was 77.8% and 52.4% respectively;and there was significant difference between both groups （P〈0.05）. The adverse effect in the treatment group was fewer and slighter than that in the control group. Conclusion Xia＇s Sleep No. 1 is effective and safe to insomnia of deficiency pattern.
出处
《中医杂志》
CSCD
北大核心
2007年第1期38-40,共3页
Journal of Traditional Chinese Medicine
