摘要
目的 探讨儿童皮肌炎／多发性肌炎（JDM／PM）的临床特点、辅助检查与治疗。方法回顾性分析本院1994年1月～2004年12月诊治的17例JDM／JPM。结果主要有肌无力、肌痛或肌压痛、关节疼痛和发热等；存在肺、心脏、胃肠道、肾损害，未见伴恶性肿瘤和钙质沉着者；LDH、HBDH、AST、CPK、α2、γ球蛋白升高，HB降低，ESR增快，RF阳性；EMG示肌源性改变，肌活检异常。结论本病以肌肉症状最多见，肌酶升高显著，以心、肺损害多见，经激素治疗均有所缓解，预后较好。
Objective To study the clinical characteristics,auxiliary examination and treatment of juvenile dermatomyositis/ polymyositis （JDM/PM）. Methods 17 hospitalized cases suffering from JDM/PM in our hospital from January,1994 to December,2004 were studied retrospectively. Results The patients with JDM/PM manifested muscle weakness, myalgia, arthralgia and fever. Although lungs, heart, gastrointestinal tract,and kidney were involved,there was no complicated with malignancy and calcinosis. In abnormal laboratory data, there were LDH, HBDH, AST, CPK, alpha-2 and gamma globulins, HB, ESR and RF. EMG revealed myogenic damage and there was abnormal muscle biopsy. Conclusion The muscle symptom is the commonest in the JDM/ PM patients, there were significant elevation of serum muscle enzymes. The pulmonary and cardiac involvements are predominant in the cases. They were relieved after treated with glucocorticoid and the prognosis is good.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2007年第2期99-101,共3页
The Chinese Journal of Dermatovenereology
