摘要
目的探讨药物性腹泻与乳糖酶含量或活性的关系，为临床治疗提供依据。方法采用尿半乳糖测试盒对80例婴幼儿进行测试，其中44例治疗组静脉滴注抗生素前无腹泻而静脉滴注抗生素后出现腹泻，36例对照组未用药无腹泻或轻度腹泻的病人进行尿半乳糖测定。结果用药组乳糖酶缺乏或活性减低，乳糖不耐受阳性率81．8％，对照组乳糖酶缺乏或活性减低，乳糖不耐受阳性率27．8％，两组差异有显著统计学意义（x^2=23．65，P≤0．01）。结论药物性腹泻婴儿的乳糖酶含量或活性减低，对乳糖不耐受。
Objective This paper aims to probe into the relationship between medical diarrhea and the amount of lactase or activity in order to provide evidence for clinical treatment. Methods Methodology adopted is test of emiction galactosylglucose. The subjects are 80 infants. And 44 of them appear diarrhea after intravenous drip antibiotic, which is opposite to their state before intravenous drip antibiotic. And 36 infants who do not appear or slightly appear diarrhea are tested with emiction galactosylglucose. Results Infants who use medicine lack of lactase or have decreased activity and the rate of lactose＇s not resisting masculine is 81.8%. The control group appears insufficient in lactase or decreased activity and the rate of lactose＇s not resisting masculine is 27.8%. The differences between these two groups are statistically significant. （X2 =23.65 ,P≤0. 01 ）. Conclusion Infants who have medical diarrhea show insufficient lactase or decreased activity and can not resist lactose.
关键词
药物
腹泻
乳糖酶
Drug Diarrhea Lactase
