摘要
目的评价一水乳梨醇（Lactitolum Monohydrate）散剂治疗慢性肝性脑病临床有效性和安全性。方法50例慢性肝性脑病病人被随机分成两组：治疗组26例，每天接受一水乳梨醇散荆10g和乳果糖口服液模拟剂10mL治疗。对照组24例，每天接受乳果糖口服液10mL和一水乳梨醇散剂模拟剂10g治疗。在实验开始时和实验的d3，d7．d10、d14检测病人血氨、数字连接试验和精神状态等指标。结果一水乳梨醇治疗慢性肝性脑病与乳果糖疗效相当（P〉0．05）。结论一水乳梨醇治疗慢性肝性脑病临床疗效明显，不良反应少，值得推广应用。
Objective To evaluate the efficacy and safety of Lactitolum Monohydrate in treatment of chronic hepatic encephalopathy. Methods 50 patients with chronic hepatic encephalopathy were separated into two groups at random： treatment group （n=26）, received Lactitolum Monohydrate 10g in a bag and simulated fluid of Lactulose 10mL in a bottle per day; control group （n=24）, received Lactulose 10mL in a bottle and Lactitolum Monohydrate simulator 10g in a bag per day. Blood ammonia, number conjunction time （NCT）, Psychomotor performance tests were observed at the beginning and the 3th, 7th, 10th, 14th day of treatment. Results There was no difference in efficacy and safety between two groups. Conclusions Lactitolum Monohydrate can be used to in the treatment of chronic hepatic cncephalopathy effectively and safely.
出处
《世界感染杂志》
2007年第1期42-45,共4页
World Journal of Infection
关键词
一水乳梨醇
慢性肝性脑病
乳果糖
Lactitolum Monohydrate
Hepatic Encephalopathy
Lactulose
