应用噬菌体报告系统快速检测结核分枝杆菌的药物敏感性
被引量:1
摘要
早期诊断耐药结核分枝杆菌是防治耐药结核病的关键和基础。1993年起噬菌体报告系统(LRPs)陆续应用于结核分枝杆菌的鉴定及耐药检测,噬笛体生物扩增法(PhaB)也在国内被用于检测结核分枝杆菌的耐药性。我们利用新的重组噬菌体phAE142建立LRPs检测方法,检测了106株结核分枝杆菌对4种常用抗结核药物的耐药性,评价LRPs在结核病临床和流行病学研究中应用的可行性。
出处
《中华结核和呼吸杂志》
CAS
CSCD
北大核心
2007年第2期154-155,共2页
Chinese Journal of Tuberculosis and Respiratory Diseases
基金
上海市科学技术委员会资助项目(05DZ22320
05PJ14025)
上海市医学重点学科资助项目(05Ⅲ029)
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