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同种睾丸Leydig细胞移植治疗男性性腺功能低下症 被引量:14

Therapy of male hypogonadism with homotransplantation of human leydig cells
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摘要 将成人睾丸Leyding细胞分离,纯化,体外培养后,按每个受者给予2×10^07个Leyding细胞给9例男性性腺功能低下症患者术后血睾酮水平均明显升高,其中6例达到正常水平,9例患才均有不同程度的男性性功能改善,3例患者男性第二性征恢复。 Adult human leydig cells to the number of 2×10~7 cultured in vitro were collected and injected into the musculi vastus medialis in patients with hypogonadism due to various causes. No immunosuppressive agent was used in all cases after transplantation.Results showed that all patients had a significantly increased level of serum testosterone and improved male sexual poten- cy,and that 3 of them appeared to recover the secondary sexual characters.It is suggested that the transplantation of human leydig cells was a new,effective treatment for male hypogonadism.
出处 《中华器官移植杂志》 CAS CSCD 1996年第3期105-107,共3页 Chinese Journal of Organ Transplantation
关键词 Leyding细胞 细胞移植 男性 性腺功能低下 治疗 Leydig cell Transplantation Male hypogonadism
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