摘要
以2，3，4-三氟硝基苯为原料，乙醇为溶剂，在催化剂作用下经还原合成2，3，4-三氟苯胺。并对其合成工艺中的影响因素进行研究，获得最佳工艺条件为：反应温度65—70℃，氢气压力0．1-0．2MPa，m（2，3，4-三氟硝基苯）：m（自制催化剂）=70．8：1．0。在此最佳工艺条件下，得到的产品纯度为99．3％，收率达97．5％。
2,3,4-Trifluoroaniline was synthesized from 2,3,4-trifluoronitrobenzene in the medium of ethanol with Raney-Ni as catalyst. The factors influencing on the synthetic process were investigated and the optimum conditions were obtained, i.e. the mass ratio of 2,3,4-trifluoronitrobenzene to self-made Raney-Ni catalyst was 70. 8： 1.0, reaction tem- perature of nitration was 65 -70℃, the pressure of hydrogen was 0. 1 ~ 0. 2 MPa. Under the optimum conditions, the final 2,3,4-trifluoroaniline product could he obtained with purity of 99. 3% , the yield was 97. 5%.
出处
《精细与专用化学品》
CAS
2007年第3期18-20,共3页
Fine and Specialty Chemicals
