摘要
目的：比较酮咯酸与强痛定对癌痛的镇痛效果及不良反应。方法：６２例癌痛病人（男性４４例，女性１８例，年龄５３±ｓ１４ａ），中度疼痛２５例，重度疼痛３７例，随机分为酮咯酸组（酮咯酸３０ｍｇ，ｉｍ，ｑ６ｈ）和强痛定组（强痛定１００ｍｇ，ｉｍ，ｑ６ｈ），２组各用药３ｄ，再交换用药３ｄ。结果：两者对癌痛的镇痛总有效率及不良反应发生率无差异；前者起效时间晚于后者，无痛维持时间长于后者。结论：酮咯酸与强痛定均为癌症疼痛有效药物。
AIM:To compare the analgesic effects and adverse reactions between ketorolac and Qiang-Tong-ding.METHODS:Sixty-two cancer patients(M 44,F 18,age 53 ± s 14) suffering from pain(moderale pain 25,and severe pain 37),were randomly divided into 2 groups:Ketorolac(30 mg,im,96h)and Qiang-tong-ding(100 mg,im,q6h)groups. Thirtyone patients received ketorolac in first 3 d and Qiang-tong-ding in next 3d, while another 31patients received Qiang-Tong-ding first 3 d and kelorolac in the next 3 d,RESULTS:The pain relief rates and adverse reactions were not much different between two groups. The time to effectiveness and the duration of pain relief in ketorolac group were longer than those in Qiang-tong-ding group.CONCLUSION : Ketorolac and Qiang一tong一ding are useful analgesics,theduration of pain relief of ketorOlac is superior to Qiang-tong-ding.
出处
《新药与临床》
CSCD
北大核心
1996年第6期335-336,共2页
关键词
酮咯酸
肿瘤
止痛
强痛定
癌痛
ketorolac, neoplasms, analgesia, Qiang-tong-ding, intractable pain
