摘要
目的比较全身用甲基强的松龙与地塞米松治疗哮喘急性发作的疗效。方法40例哮喘持续状态患者分为两组。治疗组(甲强组)给予甲基强的松龙80-160 mg/次.分2次应用。对照组(地米组)20例给予地塞米松10-20 mg/次用法同治疗组。结果治疗组患者哮鸣音消失时间显著短于对照组(P<0.01)。治疗组患者治疗72小时后PEFR恢复显著高于对照组(P<0.05)。结论治疗哮喘急性发作首选甲基强的松龙,疗效快,效果好,副作用少。
Objective To investigate the therapeutic effects of methylprednisolone and dexamethasone on acute episode of asthma. Methods Total of 40 patients with acute episode of asthma was divided into two groups. Twenty cases received methylprednisolone once 80 -160 rag,twice a day. The other twenty cases received dexamethasone once 10 - 20 mg with same useage as in the treatment group. Result The elimination time of wheezing tale in treatment group was significantly lower than that in the control group （P 〈 0. 001 ）, and the PEFR after 3 days in the treatment group was higher than that in the control group significantly （ P 〈 0. 05 ）. Conclusion Methylprednisolone could be used as the first choice of glucocortieoids because it has significantly and fleetly effect with less side effect in treating acute episode of asthma.
出处
《临床肺科杂志》
2007年第3期222-223,共2页
Journal of Clinical Pulmonary Medicine
