摘要
目的探讨早期干预对新生儿缺氧缺血性脑病(HIE)神经行为预后的影响。方法将100例HIE患儿随机分为2组,非早期干预组行一般治疗,早期干预组自出生后510d即采用医院和家庭相结合的方式从视、听、触等各方面给予一定的刺激至24个月,参照《新生儿行为与03岁潜能开发指南》制定干预措施,应用《新生儿20项神经行为评分》和《06岁儿童心理发育量表》进行评定。结果早期干预组在21d时新生儿20项神经行为评分(NBNA)和6,12,18,24个月时发育商(DQ)均比非早期干预组高16%以上(P<0·05)。结论通过早期干预能够有效的预防HIE患儿神经行为后遗症的发生。
Objective To discuss the influence of early intervention on nerve behavior prognosis of newborns with hypoxic-ischemic encephalopathy（HIE）. Methods 100 newborns with HIE were divided into two groups randomly. The infants of intervention group had been receiving continual provocation including watching, listening, touching and so on from postnatal 5-10th day up to 24th month in hospital or at home. Those in another group only accept general treatment. The intervention schemes were formulated in according with ＂Guidebook of Newborns＇Behavior and Potential Develop with 1-3Years Old＂. The therapeutic efficacies were evaluated according to ＂20 Nerve Behavior of Newborns Assessing＂ and ＂Psychological Develop Measure Form of 0 ～ 6 Years Old Child＂. Results 20 nerve behavior of newborns assessing （NBNA） on 21 th day and the development quotients （DQ） in 6, 12,18 and 24th month in intervention group were obviously higher than those in control group（ P 〈 0.05 ）. The sequelae rates （4%）in intervention group were significant lower than those（ 16% ） in another group （P 〈0.05 ）. Conclusions Early intervention could prevent newborns with HIE from nerve behavior sequelae.
出处
《实用全科医学》
2007年第1期25-26,共2页
Applied Journal Of General Practice
基金
衡水市2006年科研基金项目(编号:06008A)
关键词
早期干预
缺氧缺血
神经行为预后
Early intervention
Hypoxic-iscbemic encephalopathy
Prognosis of nerve behavior
