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颈动脉病变与前循环梗死亚型关系 被引量:8

Association of the carotid artery affection with the subtype of anterior-circulation infarction
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摘要 目的研究颈动脉病变与前循环梗死亚型之间的关系。方法采用彩色多普勒超声对116例颈内动脉系统脑梗死患者双侧颈总及颈内动脉进行探查,观察颈动脉病变特点,分析不同类型粥样斑块与脑梗死亚型的相关性。结果①68·2%的脑梗死患者存在不同程度的颈动脉病变,69·8%的患者颈动脉轻度狭窄;②左侧半球梗死的患者其同侧颈动脉粥样斑块数量远大于对侧,右侧半球梗死的患者其同侧斑块数量也大于对侧(P<0·005),同时随着颈部病变血管和斑块数量增加,颅内病变范围及程度也增加(P<0·005);③皮质支及动脉主干型脑梗死患者中不稳定性斑块35例,稳定性斑块9例;中央支梗死、分水岭区梗死及白质损害患者中不稳定性斑块分别为5例、4例、9例,稳定性斑块为17例、7例、20例。结论①颈内动脉系统病变与前循环梗死相关,同时颈动脉狭窄程度并不是前循环梗死唯一相关因素,颈动脉粥样斑块性质可能与其密切相关;②颈动脉病变与颅内病灶存在对应关系,同时颈动脉粥样硬化的程度和范围与脑梗死的程度相关,而且Willis环不仅对脑血流供应起调节和代偿作用,同时也促使微血栓向对侧及其他血管转移;③不稳定性斑块与皮质支脑梗死及动脉主干型脑梗死相关而稳定性斑块则与中央支脑梗死、分水岭区梗死及弥漫白质损害相关。 Object To study the relationship between the carotid artery affection and the subtype of anterior-circulation infarction. Methods The common and internal carotid artery of 116 cases suffered cerebral infarction in carotid artery system were examined by color ultrasound. Research the characteristic of carotid artery affection and analyse the relationship between the different type of atherosclerotic plaques and the subtype of brain infarction. Results (1) The 68. 2% of the patients suffered cerebral infarction existed a different degree of carotid artery affection. 69. 8% of the patients had slight stricture of their carotid artery. (2) The patients with the left-cerebrum infarction were found to have more plaques in their left-carotid artery than their rights. And the same conditions were found in the ritht-cerebrum infarctions ( P 〈 0. 005 ). With the increase of the carotid artery affection and plaques, there were larger areas of infarction in those patients ( P 〈 0. 005 ). (3) There were 35 unstable plaques and 9 stable plaques in infarctions with the cortical branch and the stem of the artery. The unstable plaques were 5 cases ,4cases and 9cases in the central branch infarction, cerebral wastershed infarction and the white matter harmness respectively. The stable plaques in these patients were 17 cases ,7cases and 20cases. Condusions (1) There is a reletionship between the affection of carotid artery system and the anterior-circulation infarction. And the anterior-circulation infarction had a relation not only with degree of the carotid artery stricture but also with the type of athernsclerotic plaques. (2) There is a reletionship between carotid artery affection and the brain infarction. The severity of infarction was dependent partly on the degree of atherosclerotic. The circle of Willis not only regulates the blood supply in brain,but also precipitated the micro-thrombus transferred from the blood vessel to others. (3) There exists relationship between the unstable plaqu
出处 《中国神经精神疾病杂志》 CAS CSCD 北大核心 2007年第1期23-26,共4页 Chinese Journal of Nervous and Mental Diseases
关键词 动脉粥样硬化 颈动脉 脑梗死 Atherosclerotic Carotid artery Brain infarction
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