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强直性脊柱炎治疗现状及其进展 被引量:17

The present status and progress of treating ankylosing spondylitis
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摘要 强直性脊柱炎(AS)是一种以累及脊柱和骶髂关节为特征的系统性炎性疾病。随着对AS致病因素研究的深入,虽然对其致病机制仍未完全明了,但在治疗方面,除了传统的治疗措施的研究,近年来其治疗的新策略也取得了可喜的新经验,尤其是在生物制剂方面的研究更是有了进一步的了解,并展现出良好的应用前景。 Ankylosing spondylitis (AS) is a systemic inflammatory disease characterized by involvement of spines and sacroiliac joints. Although researhes about susceptible AS factors hasn' t elucidated the pathogenic mechanism, they brought new strategies especielly biological agents such as TGF-α antagonist in treating AS on the base of the traditional therapies, Due to the significantly benifical effects of these new agents, further elincal applications may reveal a promising prospect.
出处 《国际内科学杂志》 CAS 2007年第1期39-42,60,共5页 International Journal of Internal Medicine
基金 国家杰出青年基金(基金号:30305019)
关键词 强直性脊柱炎 非类固醇类抗炎药 甲氨蝶呤 肿瘤坏死因子Α 治疗 Ankylosing spondylitis Non-steroidal anti-inflammatory drug Methotrexate Anti-TNF-α Therapy
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