摘要
The title Schiff base compound, C19H19N3O3, a derivative of antipyrine, has been synthesized and characterized by elemental analysis, IR, and single-crystal X-ray diffraction. The crystal belongs to the monoclinic system, space group C2/c, with α = 27.935（5）, b = 7.553（1）, c = 16.692（3） A, β = 105.810（3）°, Z = 8, V= 3388.7（10） A^3, Dc = 1.323 g/cm^3, Mr = 337.37, λ（MoKα） = 0.71073 A,μ= 0.091 mm^-1, F（000） = 1424, R = 0.0630 and wR = 0.1273. A total of 3513 unique reflections were collected, of which 2112 with I 〉 2σ（I） were observed. The molecular structure adopts a trans configuration about the C=N double bond. The pyrazoline and C（1）-C（6） phenyl ring are approximately coplanar （mean deviation from the combined plane is 0.069（3） A）, with the dihedral angle of 9.7（2）°. The preliminary biological tests show that the compound has high antibacterial activities.
The title Schiff base compound, C19H19N3O3, a derivative of antipyrine, has been synthesized and characterized by elemental analysis, IR, and single-crystal X-ray diffraction. The crystal belongs to the monoclinic system, space group C2/c, with α = 27.935（5）, b = 7.553（1）, c = 16.692（3） A, β = 105.810（3）°, Z = 8, V= 3388.7（10） A^3, Dc = 1.323 g/cm^3, Mr = 337.37, λ（MoKα） = 0.71073 A,μ= 0.091 mm^-1, F（000） = 1424, R = 0.0630 and wR = 0.1273. A total of 3513 unique reflections were collected, of which 2112 with I 〉 2σ（I） were observed. The molecular structure adopts a trans configuration about the C=N double bond. The pyrazoline and C（1）-C（6） phenyl ring are approximately coplanar （mean deviation from the combined plane is 0.069（3） A）, with the dihedral angle of 9.7（2）°. The preliminary biological tests show that the compound has high antibacterial activities.
基金
This work was supported by the Qufu Normal University
