摘要
目的:对比分析不同时期重度子痫前期的临床资料,探讨早发型重度子痫前期的特点。方法:回顾分析1996年1月至2005年6月广州医学院第二附属医院收治的146例单胎重度子痫前期患者的临床资料,按重度子痫前期发病孕周分为≤34周的早发组20例,>34周的晚发组126例。比较两组孕妇基本情况、生育史、部分临床项目及辅助检查结果、围生儿情况。结果:(1)两组中有定期产前检查者比例、初产妇比例、孕妇有自觉症状者的比例、并发症发生率差异有统计学意义(P<0.05)。初孕妇比例差异无统计学意义(P>0.05)。两组发生胎儿生长受限(FGR)比例、低体重儿比例、死胎比例组间比较差异均有统计学意义(P<0.05);围生儿性别男女比例早发组0.82,晚发组0.97。(2)多因素logistic回归分析显示,早发型重度子痫前期与孕妇有无正规产检、是否发生并发症相关,而与是否为初产妇无关。FGR发生与子痫前期的发病孕周呈正相关,与孕妇血红蛋白量呈负相关,而与孕妇尿蛋白量、血清白蛋白量无关。结论:重度子痫前期在不同孕周的妊娠结局有差异。早发型重度子痫前期可视为一种特殊类型的子痫前期。
Objective：To study on the characteristics of early onset severe pre-eclampsia by comparing the data observed at different gestational weeks. Methods：One hundred and forty-six cases meeting the criteria of severe pre- eclampsia were enrolled in this study. Patients were divided into 2 groups： early onset group （n =20） with those onset ≤ 34 weeks of gestation and late onset group （n = 126）with onset 〉34weeks of gestation. The basic data of gravidas, child bearing history, medical examination results, and outcome of the perinatal were compared of the two groups. Results：There were less gravida in early onset group than in late onset group who had standard antenatal care. Percentages of primipara, and those who had discomfort were different between the two group （ P 〈 0. 05 ）. The incidence of complication and FGR,low birth weight infant and perinatal mortality were also different between the two group. The male-to-female ratio of babies was 0. 82 and 0. 97 respectively in the two groups. There were no obviously difference of the ratios of the primigravida between the two groups. Whether be a primipara was no associated with the early onset severe pre-eclampsia. Conclusion： Onset of severe pre-eclampsia different gestational week may have difference outcomes. The early onset severe pre-eclampsia may be regarded as a special type of severe pre-eclampsia.
出处
《广州医学院学报》
2006年第5期7-10,共4页
Academic Journal of Guangzhou Medical College
关键词
高血压
妊娠性
先兆子痫
特点
类型
hypertension
pregnancy-induced
pre-eclampsia
characteristic
type
