摘要
目的探讨抑郁障碍患者睡眠脑电图的变化。方法应用多导睡眠生理仪,采用眼电图和下颌肌电图及脑电图等技术,对21例抑郁障碍患者的睡眠脑电图(PSG)进行整夜监测,并与22名正常受试者对照。结果抑郁障碍组PSG主要指标表现为睡眠维持率下降(正常组99%±3%,抑郁障碍组90%±5%,P<0.01),第二阶段睡眠降低(正常组57%±5%,抑郁障碍组45%±17%,P<0.05)及快眼动睡眠(REM)睡眠参数存在变异。结论抑郁障碍患者具有PSG多项睡眠脑电指标的改变。其中REM变化是本病的特点。
Objective： To assess the changes on the whole night polysomnography （PSG） in patients with depression disorder. Methods： The whole night PSG was recorded from 21 patients with depressive disorder, and 22 normal subjects, with Neurofax - 1518K （Nihon Kohden） sleep instrument. Results： Compared with normal subjects, depression disorder patients showed, reduced sleep maintenance （NC： 99 ± 3% , depression disorder group： 90 ± 5% , P 〈 0.01 ）, and decreased stage 2 sleep （ NC： 57% ± 5% , depression disorder group ： 45% ± 17%, P 〈 0.05 ）. Conclusion： Patients with depression disorder exhibit abnormality in sleep continuity; sleep frame, and rapid eye movement.
出处
《上海精神医学》
2006年第6期344-345,348,共3页
Shanghai Archives of Psychiatry
关键词
抑郁障碍
睡眠脑电图
快眼动睡眠
Depressive disorder Polysomnography Rapid eye movement
