摘要
目的：研究肾茶（Clerodendranthus spicatus）地上部位的水溶性成分。方法：应用大孔吸附树脂层析，硅胶柱层析。反相柱层析和Sephadex LH-20柱层析等多种方法进行分离纯化，通过波谱解析和理化鉴别进行结构鉴定。结果：分离得到7个化合物，分别为：咖啡酸（caffeic acid，1）、迷迭香酸（rosmarinic acid,2）、迷迭香酸甲酯（methyl rosmarinate，3）、紫草酸单甲酯（methyl lithospermate，4）、紫草酸二甲酯（dimethyl lithospermate，5）、特草酸乙单甲酯（methyl lithospermate B，6）、紫草酸乙二甲酯（dimethyl lithospermate B，7）。结论：化合物3—7均为首次从该植物中分得。
AIM： To study the water-soluble constituents of the aerial paris of Clerodendranthus spicatus. METHOD： The water soluble fractions were subjected to a series of chromatographic separation methods to afford six caffeic acid depsides, as well as free caffeic acid. Their structures were elucidated mainly by spectroscopic methods. RESULT： Seven compounds： caffeic acid （1）, rosmarinic acid （2）, methyl rosmarinate （3）, methyl lithospermate （4） and dimethyl lithospermate （5）, methyl lithospermate B （6）, dimethyl lithospermate B （7） have been isolated from Clerodendranthus spicatus. CONCLUSION： Compounds 3 - 7 have been isolated from this plant for the first time.
出处
《中国天然药物》
SCIE
CAS
CSCD
2007年第1期27-30,共4页
关键词
肾茶
多酚类化合物
缩酸
Clerodendranthus spicatus
Polyphenolic constituents
Depsides
