摘要
目的调查系统性红斑狼疮合并感染的临床特点。方法对213例系统性红斑狼疮(SLE)患者合并感染进行回顾性调查分析。结果SLE患者合并感染的发生率为39.0%;SLE合并感染的活动性部位,以肺部感染和尿路感染为主;病原菌以革兰阴性菌为主,条件致病菌相对较多;狼疮活跃、肾上腺皮质激素的使用、免疫抑制剂的应用是SLE合并感染的危险因素。结论SLE合并感染症状不典型,控制SLE合并感染要采取综合措施。
Objective： To investigate the clinical features of infection in systemic lupus erythematosus. Methods： A retrospective analysis mothod was used and the data were from 213 hospitalized patients. Results： The incidence rate of infections in systemic lupus erythematosus was 39.0%. The most common infection was in respiratory tract, followed by urinary tract. Gram - negative bacillus were the most common pathogens in infections in systemic lupus erythematosus, Fungus and Mycobacteria were also pathogens. Logistic regression analysis indicated that lupus activity, corticosteroid use and immunosuppressant use were independent risk factors of infections in systemic lupus erythematosus. Conclusions： The results showed that the clinical characters of infections were untypical. Comprehensive measures are necessary for effective prevention and control of infections in systemic lupus erythematosus.
出处
《华西医学》
CAS
2007年第1期33-34,共2页
West China Medical Journal
关键词
系统性红斑狼疮
SLE
感染
Systemic lupus erythematosus
SLE
infection
