摘要
目的了解1990至2003年细菌性痢疾的流行病学及耐药特征,为进一步采取干预措施提供科学依据。方法采用描述性研究的流行病学方法对1990至2003年痢疾发病人群进行描述;并利用 WHO 推荐的 Kirby-Bauer 法,对临床10类34种(头孢类、喹诺酮类、氨基糖甙类、大环内酯类、β内酰胺类、硝基呋喃类、糖肽类、磺胺类等)药物进行了药敏试验,通过 SPSS 软件对相关数据进行统计分析。结果北京市1990至2003年痢疾平均发病率为222.24/10万,以儿童、城区发病率为最高,发病高峰在7月16日至8月3日;获得指数曲线预测模型方程 Y=e^(5.816-0.05845X),可以用于预测菌痢的发病趋势;药敏试验分析结果表明志贺氏菌对头孢和喹诺酮类药物敏感,这两类约物中级和高级之间药敏方面没有明显差别。结论北京市近14年细菌性痢疾的疫情分析表明应针对菌痢集中及病高峰特点采取防治措施,降低发病率。
Objective To realize the epidemiological and drug-resistance characteristics of dysentery during 1990 to 2003 in Beijing. Methods The group＇s characteristics of dysentery were described and analysed by using descriptive study method. Drug sensitivity tests were performed with Kirby-Bauer method recommended by WHO, and data were analyzed with SPSS statistic software. Results Average incidence rate was 222.24/100 000 and incidence rate was high in children and in urban areas. The period of high incidence was found in July 16 to August 3. The equation of index-curve forecast model was gained as γ^=e^5.816-0.05845x. It showed some value in predicting the tendency of dysentery. Shigella was sensitive to qunolones and cephalosporins, and there was no significant differences between the middle and high grade in these two kinds of antibiotics. Conclusion It should be taken as a measurement for the period of high incidence of dysentery.
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2007年第1期54-57,共4页
Chinese Journal of Preventive Medicine
关键词
痢疾
杆菌性
综合预防
药物疗法
评价研究
Dysentery,bacillary
Universal precautions
Drug therapy
Evaluation studies
