摘要
目的探讨急性心肌梗死(AM I)溶栓后24 h内T波倒置的临床意义。方法AM I溶栓后并接受冠状动脉造影132例,根据溶栓后24 h内T波倒置与否分为T波倒置组(87例)和未倒置组(45例),观察2组冠脉再通率及住院期间左室射血分数和心血管事件。结果T波倒置组与未倒置组梗死相关动脉临床再通率分别为85.06%和35.56%,冠脉造影显示再通率分别为81.61%和26.67%,住院期间左室射血分数分别为0.56±0.11和0.42±0.13,心血管事件发生率分别为12.64%和37.78%。T波倒置组冠脉再通率和左室射血分数明显高于未倒置组(P<0.01),心血管事件发生率明显低于未倒置组(P<0.05)。结论AM I溶栓后24 h内T波倒置可作为冠脉再通的临床间接指标,同时提示更好的临床预后。
Objective To explore the clinical significance of T-wave inversion in 24 hours after thrombolysis in patients with acute myocardial infarction（AMI）. Methods 132 AMI patients who received thrombolytic therapy and coronary angiography were divided into T-wave inversion group and non-T-wave inversion group in 24 hours after the thromholytic therapy. The rate of infract correlated artery repeffusion,left ventricular ejection fraction（LVEF） and the rate of cardiac event in hospital were observed in two groups. Results The rates of infract correlated artery clinical reperfusion in T-wave inversion group and non-T- wave inversion group were 85.1% and 35.6%, the rates of infract correlated artery reperfusion through coronary angiography were 81.6% and 26.7% ,LVEF were 0.56 ±0.11 and 0.42 ±0.13 ,the rates of cardiac event were 12.6% and 37.8%. The rates of infract correlated artery reperfusion and LVEF were higher in T-wave inversion group than that in non-T-wave inversion group （ P 〈 0.01 ）, and the rates of cardiac event were lower in T-wave inversion group than that in non-T-wave inversion group （ P 〈 0.05 ）. Conclusion T-wave inversion which occurs within 24 hours after thrombolysis could be regard as an indirect index of coronary reperfusion in the patients with AMI, and it may indicate better clinical prognosis.
出处
《新乡医学院学报》
CAS
2007年第1期72-74,共3页
Journal of Xinxiang Medical University
关键词
急性心肌梗死
静脉溶栓
T波倒置
冠脉再通
acute myocardial infarction
intravenous thrombolysis
T-wave inversion
coronary reperfusion
