摘要
目的研究急性热应激和夏季飞行对飞行员血浆中主要热应激蛋白（ＨＳＰｓ）的影响。方法使用Ｄｏｔ－ｂｌｏｔ方法，分别检测飞行员在急性热应激前后和夏季飞行前后血浆ＨＳＰｓ水平。结果与应激前相比，急性热应激和飞行应激后，飞行员血浆中ＨＳＰ７０明显增加（Ｐ＜０．０５）；飞行应激后ＨＳＰ２７明显增加（Ｐ＜０．０５）。
ObjectiveToexploretheefectsofacuteheatstressandflightinhotenvironmentonplasmalevelsofheatshockproteins(HSPs).MethodsPlasmalevelsofHSP27,HSP70andHSP90weremeasuredin17pilotsbeforeandafterheatstress,and42beforeandafterflighttrainingusingdotblotmethod.ResultsComparedwiththosebeforeheatstress,HSP27,HSP90afterheatexposuretrendedtoincreasebutnonsignificant,whileHSP70increasedsigificantly.Comparedwiththosebeforeflight,HSP70togetherwithHSP27weresignificantlyincreased(P<0.05).ConclusionItissuggest-edthatthechangeofplasmaHSPslevelsmayhavesomevalueinevaluatingflightstressinhotenviron-ment.
基金
国家自然科学基金
