摘要
目的:探讨青霉素诱发癫痫样发作的作用机制及影响因素。方法:检索中国生物医学文献数据库(1978年~2006年8月)、中国医院数字图书馆(1994年~2006年6月)中报道的有关青霉素诱发癫痫的文献,对其进行汇总分析。结果与结论:检索到青霉素诱发癫痫的患者18例,既往癫痫病史、肾功能不全、老年、婴幼儿、剂量过大是诱发癫痫的主要危险因素。
OBJECTIVE: To analyze and discuss the mechanism and influencing factors associated with epileptiform seizure induced by penicillin.METHODS: Documents reporting on epileptiform seizure induced by penicillin, as recorded in CBMDisc(1978- Aug. 2006) and CHKD(1994-Jun. 2006), were sorted out and consolidated for analysis. RESULTS & CONCLUSION:Among the 18 cases of epileptiform seizure induced by penicillin, epilepsy history, renal inadequacy, old age, infants, excessive dosage were main risk factors.
出处
《中国药房》
CAS
CSCD
北大核心
2007年第2期139-140,共2页
China Pharmacy