摘要
肾动脉狭窄与进行性缺血性肾衰竭和高血压相关的心血管疾病的发病率和死亡率有着密切关系。对于此类患者的治疗现在并无确定方法。现比较各种治疗的临床研究结果。内科药物治疗是各种治疗的基础,而且仍有进一步研究的空间。目前的资料显示腔内治疗相比外科和单纯内科治疗有一定的优势,但一些特殊的病例,外科治疗仍然是很好的选择。介入治疗中一些新技术,如肾动脉远端保护装置及药物涂层支架在临床应用已有尝试,但仍处于探索阶段。目前仍需大样本多中心随机对照试验来进一步明确证明介入治疗的作用。
Renal artery stenosis is associated with morbidity and mortality consequent to progressive ischemic renal failure and the cardiovascular consequences of hypertension. There is considerable uncertainty concerning the optimal management of affected patients. This review compares the results of clinical studies. Medical therapy is the main method used. Comparing medical and surgical therapies, current data shows that there is certain predominance given to interventional therapy. Surgery is still seen as a good option. Although still the subject of research, some new techniques and instruments for interventional therapy, such as a distal protection device and drug-eluting stent, have already been used in clinic, although. The results of larger, muhicentre, randomised, controlled trials are required to clarify and support intcrvcntional therapy in renal artery stenosis patients.
出处
《心血管病学进展》
CAS
2007年第1期10-12,共3页
Advances in Cardiovascular Diseases
关键词
肾动脉狭窄
治疗
renal artery stenosis
therapy
