摘要
以Baylis-Hillman加成物为起始原料,设计并合成了5个结构新颖的4,4-二甲基异唑-3-酮衍生物。所合成的化合物经IR、1HNMR和元素分析确证。生物活性测试结果表明,所合成的目标产物在2000gai/ha的剂量下均具有较好的除草活性。中间体1-(2,4-二氯苯基)-2-溴甲基丙烯酸乙酯具有杀虫活性,在600gai/ha的剂量下对朱砂叶螨防效为100%。
Five novel 4, 4-dimethylisoxazolidin-3-one derivatives were designed and synthesized utilizing Baylis-Hillman adducts as starting materials. Their structures were confirmed by IR, ^1H NMR and elemental analysis. Evaluation of their biological activities indicated that the target compounds exhibited efficient herbicidal activity at 2000g ai/ha, while the intermediate ethyl 1-（2,4-dichlorophenyl）-2-bromomethyl-acrylate showed insecticidal activity with 100% control of tetranychus cinnabarinus at 600g ai/ha.
出处
《化学通报》
CAS
CSCD
北大核心
2006年第12期921-925,共5页
Chemistry
