摘要
目的:探讨华支睾吸虫病患者白细胞介素6(IL-6)和干扰素-γ(IFN-γ)水平的变化及意义。方法:分别采用放射免疫法和双抗体夹心EL ISA法,检测患者血清中IL-6和IFN-γ的含量。结果:华支睾吸虫病患者IL-6和IFN-γ的水平明显增高,与对照组相比有显著差异(P<0.01)。结论:华支睾吸虫病患者细胞因子网络调节功能发生紊乱,IL-6和IFN-γ参与了该病的发病过程。
Objective ：To explore the changes in the levels of interleukin--6（IL--6） and interferon--γ （IFN--γ） and their significance in patients with clonorehiasis. Methods：IL--6 and IFN--γ were examined by radioimmunoassay（RIA） and enzyme--linked immunosorbent assay（ELISA）. Results：The levels of IL --6 and IFN --γ in patients with clonorchiasis were significantly higher than those of the control group, and the differences were significant （ P〈0. 01 ）. Conclusion.There exist celluar immune function disorders in patients with clonorchiasis, and IL--6 and IFN --γ participate in the process of clonorehiasis.
出处
《黑龙江医药科学》
2006年第6期9-9,10,共2页
Heilongjiang Medicine and Pharmacy
基金
黑龙江省教育厅资助项目(No.10531152)
