摘要
抗苗勒管激素是转化生长因子-β家族成员之一,其在雄性胎儿的发育过程中引起苗勒氏管的退化。在雌性,抗苗勒管激素主要由卵巢窦前卵泡和小窦卵泡颗粒细胞分泌,与卵巢功能密切相关,是最新发现的评价卵巢年龄的重要指标,可很好地预测卵巢对促排卵药物的反应性,并和女性生殖内分泌疾病多囊卵巢综合征的发病与临床特征相关。
Anti-muellerian hormone（AMH） is a member of the transforming growth factor-β superfamily. It is named because it induces muller＇s duct degeneration in the males. In females, AMH is produced only by granulose cells in preantral and small antral follicles of ovary. Serum AMH level is associated closely with ovarian function, so it is a new marker to evaluate ovarian aging and to predict the ovary responsiveness to ovalution stimulants. In addition, it is related to development and clinical characteristics of polyeystie ovarian syndrome.
出处
《中国妇幼健康研究》
2006年第6期507-510,共4页
Chinese Journal of Woman and Child Health Research
关键词
抗苗勒管激素
卵巢功能
卵巢储备
卵巢反应性
多囊卵巢综合症
anti-muellefian hormone （AMH）
ovarian function
ovary reserve
ovary responsiveness
polycystie ovary syndrome （PCOS）
