摘要
目的探讨多序列MR扫描在心脏瓣膜病中的诊断价值。方法回顾性分析56例心脏瓣膜病患者的影像学资料,患者分别采用超声心动图(UCG)、二维(2D)黑血及亮血序列、K-空间节段真实稳态进动快速扫描序列(TrueFISP)对瓣膜病进行定性评价,15例患者还进行小角度快速激发(FLASH)电影序列和流速编码电影(VEC)定量分析,并将MR结果与UCG进行对比。结果UCG和MRI诊断二尖瓣狭窄(MS)2例,二尖瓣关闭不全(MI)23例;主动脉瓣狭窄(AS)7例,其中二瓣畸形5例;主动脉瓣关闭不全(AI)13例;三尖瓣关闭不全(TI)2例;复合或联合瓣膜病9例。受累心腔的增大和升主动脉的扩张是其主要形态学改变,异常的血液湍流信号是受累瓣膜的直接征象。VEC-MR定量分析与多普勒超声一致性好:6例AS,MR和UCG检查结果相关性分析,相关系数和校正相关系数分别为:R=0.975、Rsq=0.951(P<0.01),AI9例,分别为R=0.965、Rsq=0.932(P<0.01)。结论MR多序列综合扫描可对心脏瓣膜病特别是主动脉瓣疾病进行准确的定性及定量评价。
Objective To assess the diagnostic value of the magnetic resonance imaging (MRI) for heart valve disease qualitatively and quantitatively. Methods From 18^th Sep, 2004 to 30^th Jun, 2005, 56 consecutive patients underwent MR scanning with multiple sequences, including two-dimensional dark and bright sequences, K-space segmented TrueFISP and FLASH cine sequences, as well as velocity-encoded cine MR(VEC-MR). Morphologic and functional parameters were applied to assess the disease qualitatively and quantitatively. For quantitative analysis, Doppler echocardiography was compared to evaluate the reliability of VEC-MR in assessing the severity of aortic valve disease. Correlations coefficient was analyzed by a statistic software ( SPSS 13. 0) , P 〈 0. 05 is considered significant difference. Results Two cases with mitral valve stenosis ( MS ), 23 with mitral valve insufficiency ( MI ) , 7 with aortic valve stenosis ( AS ) including 5 with hi-valvular malformation, 13 with aortic regurgitation including 6 with Marfan's syndrome, 2 with tricuspid valve insufficiency, 9 with combined or multiple valve diseases were found in all 56 cases. The dilation of the corresponding heart chambers and ascending aorta was the main morphologic findings in valve disease, while the abnormal flow jet across the involved valve was the main positive sign in qualitative assessment of valve disease. Good correlations were obtained in AS and AI comparing with Doppler echocardiography (R =0. 975, Rsq =0. 951 ,P=0. 01 for AS and R =0. 965, Rsq =0. 932,P 〈0. 01 for AI) . Conclusion Heart valve diseases can be qualitatively and quantitatively evaluated by MR multiple sequences, especially in aortic valve disease.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2006年第12期1276-1280,共5页
Chinese Journal of Radiology
关键词
心脏瓣膜疾病
磁共振血管造影术
磁共振成像
电影
评价研究
Heart valve diseases
Magnetic resonance angiography
Magnetic resonance imaging, cine
Evaluation studies