摘要
目的及时掌握布鲁氏菌病的流行动态,为今后制定防制措施提供科学依据。方法对7例经临床诊断为布鲁氏菌病的患者进行流行病学个案调查,并对其临床资料进行分析;采用布鲁氏菌病特异性血清学进行抗体水平检测及细菌学培养与分型。结果在报告的7例布病患者中,其中本市户籍2例;外地户籍5例。男性3例;女性4例。分布在20～60岁年龄组。职业分布:实验室检验人员1例,牲畜屠宰、销售3例,其他3例(家庭主妇、商业服务、个体司机)。接触史:在牲畜屠宰、销售过程中或加工进食羊仔和羊胎盘及嗜食路边烧烤牛、羊肉串,与畜及畜产品有直接或间接接触史的占85.71%;实验室工作中不慎感染占14.29%。试管凝集试验:14∶00/2例,18∶00/3例,11∶600/3例。菌种鉴定:布鲁氏杆菌猪4型2例,羊种3型2例,另3例未上送菌种鉴定。7例布鲁氏菌病患者经治疗后痊愈。结论应提高对布鲁氏杆菌病的认识,减少误诊漏诊,在转入慢性期前及时治疗最为理想。
Objective To find out the epidcmiological dynamics of brucellosis and to provide scicntific evidence for formulating prevention and control measures in the future. Method Epidcmiological and clinical data of seven patients with clinically diagnosed brucellosis were analyzed. The level of erum antibody to brucella was mcasured using serological method, and the bacteria were identified using microbiological method. Result Of the seven patients, two （28.57%） were Guangzhou citizens and the other five （71.43%） came from other places in the country. Three patients （42.86%） were males and the other four （57.14%） were females. All seven patients belong to the age group of 20-60 years. In terms of occupational distribution, one （14.29%） was a laboratory technician, three （42.86%） were employed in livestock slaughter and sales, and the remaining three were housewife, businessman and freelance driver. With respect to the mode of transmission, 85.71% had direct or indirect contact with animals and animal products through livestock slaughtering and sales, processing and consuming of lamb and sheep placenta and indulging in roadside barbecued beef and lamb balls. 14.29% were acquired from the laboratory. In vitro agglutination test showed that two cases had a titer of 1：400, three had a titcr of 1：800 and another three had a titcr of 1：1600. Bacterial analysis revealed that two patients were infected by brucella suis type 4, and another two were infected by brucella mclitcnsis type 3. The bacterial strains isolated from the remaining three patients were not idcntified. All of the seven patients were cured after treatment. Conclusion Training in diagnosis of brucellosis should be given to medical staff. Treatment should be given to the patients before the progression of the disease into the chronic stage.
出处
《热带医学杂志》
CAS
2006年第12期1299-1300,共2页
Journal of Tropical Medicine
