摘要
目的探讨扶正化瘀平喘法对哮喘发作患儿血清白细胞介素5(IL-5)、白细胞介素8(IL-8)的影响。方法将95例哮喘发作患儿随机分为治疗组和对照组,治疗组49例采用扶正化瘀平喘法配合舒利迭治疗,对照组46例只用舒利迭。观察两组临床疗效及治疗后患儿血清IL-5、IL-8含量及肺功能变化。结果治疗组在临床疗效及降低血清IL-5、IL-8和改善肺功能方面明显优于对照组(P<0.05)。结论扶正化瘀平喘法能有效降低哮喘发作患儿细胞因子含量,缓解气道炎性反应而发挥治疗作用。
Objective:To investigate effects of method for strengthening the body resistance,removing blood stasis and relieving asthma on serum interleukin- 5 (IL- 5) and interleukin- 8 (IL-8) in asthma attack children. Methods : Ninety-five asthma attack children were randomly divided into two groups. The treatment group (n= 49) were treated with the method for strengthening the body resistance, removing blood stasis and relieving asthma combined with Flutiasone and Salmeterol dipropionate inhalation ,and the control group (n= 46) with the inhalation. Clinical therapeutic effect,changes of serum IL-5 and IL-8 contents,and pulmonary function after treatment in both groups were investigated. Results:The treatment group was superior to the control group in therapeutic effect, decrease of serum IL-5 and IL-8,and improvement of pulmonary function (P〈0.05). Conclusion:The method for strengthening the body resistance,removing blood stasis and relieving asthma can effectively decrease contents of cytokines and relieve airway inflammatory reaction in asthma attack children, which might be the cause of its effect.
出处
《中医杂志》
CSCD
北大核心
2006年第11期844-845,共2页
Journal of Traditional Chinese Medicine
关键词
哮喘/中医药疗法
IL-5/血液
@扶正化瘀平喘法
Asthma/TCM therapy
Interleukin/blood
@ method for strengthening the body resistance,removing blood stasisand relieving asthma