摘要
目的测定肝硬化患者心电图P波离散度(Pd)、QT离散度(QTd)及JT离散度(JTd)数值,探讨其临床意义。方法按Child分级标准将60例肝硬化患者分为A、B、C级三组,测量同步12导联心电图Pd、QTd和JTd数值变化以及与总胆红素、白蛋白的相关性,并与30例健康者(对照组)比较。结果肝硬化患者出现心电图改变者占61.7%,高于对照组(36.7%,P<0.05);Pd、QTd和JTd数值高于对照组(P<0.01);且三组间比较,差异有统计学意义(P<0.01);Pd、QTd和JTd与总胆红素呈正相关(P<0.01),与白蛋白呈负相关(P<0.01)。结论肝硬化患者存在着心电图的改变,Pd、QTd和JTd数值的变化可评价肝硬化的严重程度,并能了解预后及指导临床治疗。
Objective To measure P - wave dispersion, QT dispersion and JT dispersion of electrocardiogram in patients with liver cirrhosis and study the clinical significance. Methods Sixty patients were divided into three groups of A, B and C by Child grade. Measured the changes of P - wave dispersion, QT dispersion and JT dispersion of deetrocardiogram, judged the correlation to serum total bilirubin and albumin, compared to the control group. Results The 61.7% patients changed in their electrocardiogram and were higher than the 36.7% of the control ( P 〈 0.05 ) ; The number of P - wave dispersion, QT dispersion and JT dispersion of electrocardiogram in patients were higher than those in control ( P 〈 0.01 ) ; the significant difference were existed in A, B and C group ( P 〈 0.01 ) ; there were the positive correlation to serum total bilirubin and the negative to albumin. Conclusions The changes of electrocardiogram are existed in patients with liver cirrhosis. The number of P - wave dispersion, QT dispersion and JT dispersion of electrocardiogram evaluate the degree of liver cirrhosis, and can judge the prognosis and guided the clinical treatment.
出处
《中国医师进修杂志》
2006年第11期17-18,21,共3页
Chinese Journal of Postgraduates of Medicine
关键词
肝硬化
P波离散度
QT离散度
JT离散度
临床意义
Liver cirrhosis
P - wave dispersion
QT dispersion
JT dispersion
Clinical significance