摘要
目的:比较左旋布比卡因分别复合芬太尼、曲马多行术后硬膜外自控镇痛(PCEA)的临床效果。方法:PCEA60例随机等分成三组。A、B和C组均用0.15%左旋布比卡因100mL,但B组含芬太尼(4.0μg/mL),而C组含曲马多(4.0mg/mL)。PCEA参数设置:负荷剂量4mL,单次剂量3mL,锁定时间50min,持续剂量1.5mL/h。结果:A组24h用药总量及PCEA的使用次数明显高于其他两组(P﹤0.01)。而B组的PCEA各指标最低(P﹤0.01),恶心呕吐发生情况:A组0例,B组2例,C组6例。三组各发生尿潴留1例。各组RR和MAP差异无显著性(P﹥0.05)。结论:在本实验条件下,左旋布比卡因复合芬太尼PCEA的镇痛效果最好。
Objective： To compare the clinical effect of levobupivacaine alone or combined with fentanyl or tramadol for patient-continUed epidural analgesia（PCEA） after operation. Methods： 60 parturients undergoing continuous epidural anesthesia after lower extremity operations were equally and randomly divided into three groups. They all received 0.15% levobupivacaine, but group B plus fentanyl （4 μg/mL）, and group C plus tramadol （4.0 mg/mL）. The PCEA parameters of loading dose 4 mL, single 3 mL, locking the time in 50 minutes and continuous infusion with 1.5 mL/ hour were setup. Results： The total drug dosage, number of button pressed and VAS in geoup A were significandy higher than those in the other groups （P 〈 0.01）, which were lowest in group B （P 〈 0.01）, the incidence of nausea and vomiting was highest in group C. The incidence of urinary retention among 3 groups was not differnce. The statistic study in RR and MAP were not significant differnce between 3 group （P 〉 0.05）. Conclusion ：The combined with fentanyl epidural analgesia with effect of levobupivacaine is safety and credibility.
出处
《岭南急诊医学杂志》
2006年第6期440-441,共2页
Lingnan Journal of Emergency Medicine
