摘要
目的:探讨胃肠道间质瘤的临床及病理特征。方法:回顾性分析52例经病理证实的胃肠道间质瘤的临床和病理资料。结果:消化道出血(65%)是最常见的临床表现;梭形细胞型35例(67%),上皮样细胞型7例(13%),混合型10例(19%)。免疫组织化学染色CD11794%、CD3479%、SMA48%、desmin44%、S-100蛋白9.6%;良性9例(17%),交界性20例(38%),恶性23例(44%);CD117、CD34在良性、交界性、恶性间质瘤中的表达均无显著性差异(P>0.05)。结论:胃肠道间质瘤的临床表现复杂多样,误诊率高;免疫组织化学标记CD117对胃肠道间质瘤有确诊意义。
Objective： To investigate the clinical and pathological features of gastrointestinal stromal tumors （GIST）. Methods： 52 cases of GIST were retrospectively reviewed in terms of clinical and pathological features. Results： The gastrointestinal bleeding（65%） was the most common clinical manifestation. Pathologically, our study showed that 35 cases （67%） were spindle cells type, 7 cases（13%） were epithelioid cells type and 10 cases（19%） were mixed cells type. In immunohistochemistry, positive rate for CD117, CD34, SMA, Desmin and S-100 were 94.23%, 78.84%, 48.07%, 44.23% and 9.61% respectively. The pathological diagnosis showed 9 cases （17%） were benign, 20 cases （38%） were borderline, 23 cases （44%） were malignant. Conclusions： GIST has a variety of clinic manifestations and it was misdiagnosed. The detection of CD117 can confirme diagnosis.
出处
《岭南急诊医学杂志》
2006年第6期411-412,419,共3页
Lingnan Journal of Emergency Medicine
关键词
胃肠道间质瘤
临床
病理
gastriointesfinal stromal tumors
clinic
pathology
