2Sakaguchi T,Tu Q,Pinto L H,et al.The active aligomeric state of the minimalistic influenza virus M2 ion channel is a tetramer[J].Proc Natl Acad Sci USA,1997,94:5000-5004. 被引量：1
3Lamb R A,Zebedee S L,Richardson C D.Influenza virus M2 protein is an integral membrane protein expressed on the infected-cell surface[J].Cell,1985,40:627-633. 被引量：1
4Pinto L H,Holsinger L J,Lamb R A.Influenza virus M2 protein has ion channel activity[J].Cell,1992,69:517-528. 被引量：1
5Sakaguchi T,Lesser G P,Lamb R A.The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus[J].J Cell Biol,1996,133:733-747. 被引量：1
6Castrucci M R,Kawaoka Y.Reverse genetics system for generation of an influenza A virus mutant containing a deletion of the carboxyl-terminal residue of M2 protein[J].J Virol,1995,69:2725-2728. 被引量：1
7Ito T,Gorman O T,Kawaoka Y.Evolutionary analysis of the influenza A virus M gene with comparison of the M1 and M2 proteins[J].J Virol,1991,65(10):5491-5498. 被引量：1
8Black R A,Rota P A,Gorodkova N,et al.Production of the M2 protein of influenza A virus in insect cells is enhanced in the presence of amantadine[J].J Gen Virol,1993,74(Pt8):1673-1677. 被引量：1
9Zebedee S L,Lamb R A.Influenza A virus M2 protein; monoclonal antibody restriction of virus growth and detection of M2 in virions[J].J Virol,1988,62(8):2762-2772. 被引量：1
10Treanor J J,Tierney E L,Zebedee S L,et al.Passively transferred monoclonal antibody to the M2 protein inhibits influenza A virus replication in mice[J].J Virol,1990,64(3):1399-1402. 被引量：1
二级参考文献9
1[1]Black R A,Rota P A,Gorodkova N,et al.Production of the M2 protein of influenza A virus in insect cells is enhanced in the presence of amantadine[J].J Gen Virol,1993,74(Pt8):1673-1677. 被引量：1
2[2]Zebedee S L,Lamb R A.Influenza A virus M2 protein;monoclonal antibody restriction of virus growth and detection of M2 in virions[J].J Virol,1988,62(8):2762-2772. 被引量：1
3[3]Treanor J J,Tierney E L,Zebedee S L,et al.Passively transferred monoclonal antibody to the M2 protein inhibits influenza A virus replication in mice[J]. J Virol,1990,64(3):1399-1402. 被引量：1
4[4]Ito T,Gorman OT,Kawaoka Y.Evolutionary analysis of the influenza A virus M gene with comparison of the M1 and M2 proteins[J].J Virol,1991,65(10):5491-5498. 被引量：1
5[5]Slepushkin V A,Katz J M,Black R A,et al.Protection of mice against influenza A virus challenge by vaccination with baculovirus-expressed M2 protein[J].Vaccine,1995;13(15):1399-1402. 被引量：1
6[6]Neirynck S,Deroo T,Saelens X,et al.An universal influenza A vaccine based on the extracellular domain of the M2 protein[J].Nat Med,1999,5(10):1157-1163. 被引量：1
7[7]Hahnenberger K M,Krystal M,Esposito K,et al.Use of microphysiometry for analysis of heterologous ion channels expressed in yeast[J].Nat Biotechnol,1996,14(7):880-883. 被引量：1
8[8]Hennessey E S,Hashemzadeh-Bonehi L,Hunt L A,et al.Assembly of eukaryotic class Ⅲ (N-out,C-in) membrane proteins into the Escherichia coli cytoplasmic membrane[J].FEBS Lett,1993,331(1-2):159-161. 被引量：1
9[9]Frace AM,Klimov A I,Rowe T,et al.Modified M2 proteins produce heterotypic immunity against influenza A virus[J].Vaccine,1999,17(18):2237-2244. 被引量：1
2Palese P.Influenza:old and new threats[J].Nat Med,2004,12(S):82-87. 被引量：1
3Horimoto T,Kawaoka Y.Influenza:lessons from past pandemics,warnings from current incidents[J].Nat Rev Microbiol,2005,3(8):591-600. 被引量：1
4Oxford J,Lambkina R,Elliot A,et al.Scientific lessons from the first influenza pandemic of the 20th century[J].Vaccine,2006,24(45):6742-6746. 被引量：1
5Epidemic and Pandemic Alert and Response (EPR).Cumulative Number of Confirmed Human Cases of Avian Influenza A(H5N1) Reported to WHO[EB/02].Http://www.who.int/csr/disease/avian-influenza/country/cases-table-2007-04-12/en/index.html. 被引量：1
7Czabotar P E,Martin S R,Hay A J.Studies of structural changes in the M2 proton channel of influenza A virus by tryptophan fluorescence[J].Virus Research,2004,99(1):57-61. 被引量：1
8Duong-Ly K C,Nanda V,Degrado W F,et al.The conformation of the pore region of the M2 proton channel dependson lipid bilayer environment[J].Protein Sci,2005,14(4):856-861. 被引量：1
9Kass I,Arkin I T.How pH Opens a H+ Channel:The Gating Mechanism of Influenza A M2[J].Structure,2005,13 (12):1789-1798. 被引量：1
10Wu Y,Voth G A.A computational study of the closed and open states of the influenza A M2 proton channel[J].Biophys J,2005,88(4):2402-2411. 被引量：1
